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Furthermore, the initiation of this cascade is not instantaneousspanning from mitochondrial damage and the release of damage-associated molecular patterns (DAMPs) to immune cell metabolic reprogramming and the subsequent production of inflammatory mediators

Zinc has been shown to strengthen GI barrier function by supporting the structure of tight junctions

Supplementation with high doses, extended periods of supplementation, or the combination of vitamin B12 with vitamins B1, B2, or B6, were suggested as possible causal factors of acneiform eruptions [5,6]

We would also like to thank the Melbourne Mass Spectrometry and Proteomics Facility of The Bio21 Molecular Science and Biotechnology Institute at The University of Melbourne for the support of mass spectrometry analysis