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Description
Myokines, including interleukin-6 (IL-6), irisin, and brain-derived neurotrophic factor (BDNF), released in the context of muscle contraction, exert influence on CNS functioning by traversing the bloodbrain barrier (BBB) or by acting upon peripheral nerves

This means you can feel the effects of the vitamin B12 shot for up to a month
Circulation 102:351356 [DOI] [PubMed] [Google Scholar] Villarino AV, Kanno Y, OShea JJ (2017) Mechanisms and consequences of JakSTAT signaling in the immune system

& Feng, G
