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People with chronic obstructive pulmonary disease (COPD) experience long-term oxidative damage and inflammation of lung tissue, which causes airways to constrict, leading to shortness of breath and coughing

In such circumstances, the CPIC guideline recommends administration for the shortest possible duration, under expert supervision, with therapeutic drug monitoring and serial audiological assessment, recognizing that ototoxic risk remains substantial even with these precautions (McDermott et al., 2022b)

Through breeding and biotechnological methods, researchers are developing tobacco varieties with desirable traits, including low nicotine content, increased sugar accumulation, and modified cell wall composition for more efficient processing

Mahdavi A, Bagherniya M, Mirenayat MS, Atkin SL, Sahebkar A (2021) Medicinal plants and phytochemicals regulating insulin resistance and glucose homeostasis in type 2 diabetic patients: a clinical review