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There was no significant difference in lipid peroxidation between the control groups (C/VEH vs C/CBD)

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Several clinical trials are evaluating eloralintide as a monotherapy (NCT06230523, NCT06297616, NCT06916091) or in combination with the dual GIP/GLP-1 receptor agonist tirzepatide (NCT06603571, NCT06345066, NCT06916065) in adults with overweight and obesity, with or without type 2 diabetes

Nevertheless, the regulation (direct or indirect) of GPx1 by Nrf2-linked pathways is intriguing as GPx1 can modulate oxidant stress to mitigate Nrf2 activation