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The association between retraction of the torn rotator cuff and increasing expression of hypoxia inducible factor 1alpha and vascular endothelial growth factor expression: an immunohistological study
& Clarke, R
It acts more like a system-wide signal touching multiple pathways at once, which is part of why its effects are so broad and, honestly, a bit unusual for something this small

the messenger still gets the job done, but it might take a bit longer for the message to reach the repair team
