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Description
All of the substrate cobalt-corrin molecules from which B12 is made must be synthesized by bacteria
However, in patients with pernicious anaemia these assays should not be used because the intrinsic factor antibodies in the patient's serum interferes with the binding of B12 to the intrinsic factor used in the assay, generating spurious results
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doi:10.1155/2017/8025752 Jautov J, Zelenkov H, Drotarov K, Nejdkov A, Grnwaldov B, Hladikov M
