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1 Introduction The growing global burden of cancer necessitates innovative strategies that span prevention, treatment sensitization, and mitigation of therapy-related toxicity ( Epidemiological studies have consistently linked the consumption of glucoraphanin-rich cruciferous vegetables with a reduced risk of several cancers, including those of the prostate, lung, and colorectum ( The efficacy of SFN is intrinsically linked to the biosynthesis of its precursor, glucoraphanin, in the plant itself

found that, in diabetic ulcers, the levels of ROS, MDA, and lipid peroxidation in fibroblasts and vascular endothelial cells subjected to high glucose settings are significantly increased [189]

Mitochondrial superoxide: Production, biological effects and activation of uncoupling proteins

In melanoma tumors, low glutamine levels often drive the cells to an undifferentiated state