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Description
The product is a red-brown to dark brown powder, with a purity of 98% (HPLC), soluble in DMSO, and stored sealed at -20
Histopathological analyses of major organs (liver, kidneys, heart, lungs) revealed no notable structural abnormalities
Further findings indicate that in IBD, TNF- blockage has been shown to result in reduced intestinal permeability through decreased endothelial cell apoptosis and decreased permeability of tight junctions, increased Treg cell activity, reduced activity of various inflammatory mediators and T cells, and a reduction in inflammation-mediated mucosal angiogenesis by preventing the production of vascular endothelial growth factor A from intestinal fibroblasts [37,38]
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