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10.1016/j.cell.2015.04.042 Summary Keywords intervertebral disc, low back pain, MSC, regenerative medicine, microenvironment, niche, extracellular vesicles (EVs), disc progenitor cells Citation Wang H, Xu A, Hua W, Mao J, Zhang J, Ma X and Lu L (2025) Stem cell-based strategies for intervertebral disc regeneration in degenerative microenvironments: challenges and solutions

This study identified a novel mechanism through which TSA exerts anti-atherosclerotic effects via the LOX-1/NF-B axis

3 Prevention and treatment interventions 3.1 Lifestyle and dietary interventions Considering the lack of current treatments for PD beyond symptom management, and the growing evidence of MetS and NBD being intertwined, lifestyle and dietary modifications have been taken into account as a potential part of the treatment
