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Treatment of HCC cells with ADI-PEG20 downregulates the key enzymes of pyrimidine synthesis in the TCA cycle, carbamoyl phosphate synthetase 2, thymine synthase (TS), aspartate transcarbamylase and dihydrooratase (CAD) and malate dehydrogenase 1 (MDH-1) activities, making tumor cells more susceptible to 5-fluorouracil (5-FU)
Volume 2024
InEmerging issues in the water environment during Anthropocene: a South East Asian perspective Aug 29 (pp
Harvey CJ, Thimmulappa RK, Sethi S, et al
