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Expecting immediate results can lead to premature conclusions and disappointment, so its best to plan for longer-term observation in any research setting

The biological plausibility of AOD9604s cartilage-regenerating effects is further supported by insights from conditions such as acromegaly, where excess GH leads to abnormally thick cartilage due to elevated local IGF-1 production

Because that figure comes from rodent research, many start patients at the low end (about 5 mcg/kg or a flat 250 mcg) and adjust over one to two weeks

Finally, NR administration in old mice showed a small but significant increase in lifespan (5%) 198