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Description
Pegtibatinase, also known as OT-58 or TVT-058, is a recombinant human CBS catalytic core (amino acids 1413) that has been modified with the addition of polyethylene glycol (PEG) and lacks the CBS autoinhibitory regulatory domain, yielding a constitutively active, predominantly dimeric enzyme
Pharmaceutics 14 , 404 (2022)
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