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90,91 Additionally, the activity of epigenetics-modifying enzymes and their cofactors, such as TET and -ketoglutarate (-KG) from the tricarboxylic acid cycle (TCA), can be influenced by abnormal metabolite levels in patients with metabolic diseases, further disrupting epigenetic regulation and exacerbating disease progression
Cytokine alterations in schizophrenia: an updated review
RAS affects a large proportion of the population and has a point prevalence of approximately 23%, daily
When intracellular GSH levels decrease, GPX4 activity declines, allowing lipid peroxides to accumulate
