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doi: 10.1016/j.aqrep.2023.101585 39 ChenX.LiP.HouD.LiM.ChenB.PengK.et al

( 3.1.4 Nrf2/Slc7a11/GPX4 axis and myocardial injury In ischemia-reperfusion injury (IRI), a well-established model for myocardial injury, ozone pre-treatment mitigates myocardial ferroptosis by activating the Nrf2/solute carrier family 7 member 11 (Slc7a11)/GPX4 axis

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The sustained levels may also increase the likelihood of certain side effects, particularly joint stiffness and water retention