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In Pompe disease, a rare lysosomal disorder, NAC was identified as an allosteric chaperone for the lysosomal enzyme -glucosidase [84]
inhibited the activation of TGF-1/Smad signaling pathway
[DOI] [PubMed] [Google Scholar] 5.Mnzo Y., Lichtblau I., Elder K
Furthermore, pro-inflammatory cytokines can damage mitochondria and aberrantly increase mtROS production (Lin et al., 2022)
