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Funct Foods Health Dis 12:198207 Otvos L Jr (2008) Peptide-based drug design: here and now

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FIGURE 1 5 Multiple cell ferroptosis promotes atherosclerosis 5.1 Ferroptosis of vascular endothelial cells promotes atherosclerosis AS begins with vascular endothelial dysfunction, characterized by increased permeability, leukocyte adhesion, heightened inflammation, and accelerated plaque and thrombus formation

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Yet, there remains uncertainty about the sequence and direction of events, i.e., which are upstream or downstream, and which may be hubs for intersecting spokes

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