nac and glutathione synthesis N-Acetylcysteine (NAC): Impacts on Human Health Novel Synthesis of N-Acetylcysteine Medicine

[DOI] [PubMed] [Google Scholar] 148.Percrio S., Barbosa A.S., Varela E.L.P., Gomes A.R.Q., Ferreira M.E.S., Moreira T.N.A., Dolabela M.F

2020;368 doi: 10.1126/science.aaw5473

In particular, Arsenic is a semi-metal with a complex ambivalent biochemical behavior: it is both a recognized human carcinogen and a curative anti-leukaemia drug and in both phenomena, its binding with cellular bio-thiols such as glutathione and with protein thiol groups is essential

These include poor dietary habits, life-stages and/or lifestyles either limiting intakes or increasing micronutrient requirements (e.g., smoking and alcohol or drug abuse), various diseases, exposure to pollutants and smoke (both active and passive), and economic reasons (poor socioeconomic status and limited access to nutritious food) [15,16]