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Preclinical studies report higher mitochondrial DNA copy numbers and elevated respiratory enzyme levels in muscle tissue, correlating with increased VOmax and reduced fatigue in rodent exercise tests

Its mechanism is confined to pineal/circadian signalling and TERT gene expression, making it pharmacologically distinct from GH secretagogues

Tendon and ligament healing Due to a limited blood supply, the spontaneous healing of both tendons and ligaments is inherently poor
