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Protect from excessive heat and direct sunlight
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(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-B activation

This ATF4-mediated induction is often triggered by the GCN2-eIF2 pathway when uncharged tRNAs accumulate (a sign of amino acid deprivation) [23]