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However, the impact of B12 supplementation on mitochondria biology and the mechanism(s) in which B12 affects skeletal muscle have not been elucidated

By targeting and inhibiting the function of SLC7A11, sulfasalazine can effectively reduce the neurodegenerative phenotype of glioma cells and their microenvironmental toxicity [52]

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Under homeostatic conditions, Nrf2 is bound to Kelch-like ECH-associated protein 1 (Keap1) and targeted for degradation through ubiquitination (McMahon et al., 2006)
