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Table 1 lists 46 compounds that displayed statistically significant ( 1.5x) shifts in abundance during 58 hr of fasting, whose calculated formal powers were shown in Table S2: among 46 metabolites, the statistical power for 38 compounds was found to be rather high (more than 0.8)
While tirzepatide does not directly affect thyroid function, the caloric deficit it produces creates similar metabolic pressure
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