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J Curr Ophthalmol (2022) 34(1):1624
The reduction of PTTG1 and PTTG2 at the protein level was checked by immunoblotting using extracts of HCT116 cells infected with lentivirus expressing shPttg1, shPttg2 or empty vector and specific PTTG1 and PTTG2 antibodies (Figure 1c, left panel)

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While the ultimate cause of this zinc imbalance remains to be fully elucidated yet, a dysregulation in various metal storage and transport proteins is likely [337]
