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Lipid Peroxidation: Polyunsaturated fatty acids (PUFAs), especially arachidonic and adrenic acids, are substrates for lipoxygenases (LOX), which drive peroxidation in membrane phospholipids, generating cytotoxic lipid peroxides such as 4-hydroxynonenal (4-HNE) and malondialdehyde (MDA) (Hasan et al., 2023)

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In compliance with the relevant FDA and EMA guidelines [911], for each of the two test liquid formulations, bioequivalence was concluded if the 95% CIs for the estimated test/reference ratios of geometric means of AUC 0-t and C max were within the standard pre-specified acceptance range for bioequivalence (0.80-1.25)

Total cholesterol levels fell by approximately 30%