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Description
Mutations in the PHGDH gene are associated with a rare autosomal recessive disorder characterized by presentation in infancy with microcephaly, intractable seizures, and little to no psychomotor development
M.HanL.ZhangT
Beyond direct radical neutralization, -TOH also plays a significant part in suppressing ROS generation by inhibiting NADPH-OX isoforms, particularly NADPH-OX2 and NADPH-OX4, which are up-regulated during seizure-induced glutamate excitotoxicity [49]
Food Science and Biotechnology , 12 , 476479
