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References Maar K, Hetenyi R, Maar S, Faskerti G, Hanna D, Lippai B, Takatsy A, Bock-Marquette I

In vitro studies examining receptor-independent growth hormone signalling
acnes caused by B12 supplements encourages the growth of a pigment called porphyrins, which further contributes to the inflammation associated with acne (11)

Some fertility problems are due to a woman having trouble producing LH
