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Herbal Compounds for the Treatment of Vitiligo: A Review

Other target organs included kidney (increased weight, glomerular and tubular epithelial swelling, pigmentation of tubular epithelial cells), nasal epithelium (glandularization of the respiratory epithelium, pigment deposition in and degeneration of olfactory epithelium), thyroid (follicular cell hyperplasia), thymus (involution) and pancreas (mononuclear cell infiltration), while lung pathology (emphysema, atelectasis and bronchiolization of alveolar cell walls) was reported in rabbits

Numerous candidates with different molecular targets and mechanisms of action are being characterized in obesity models with the aim to demonstrate in vivo preclinical proof-of-concept

Therefore, the GST enzyme and Se play an important role in vivo in the metal detoxification process