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It turns out that even in mice that lack these receptors, fat loss takes place when AOD9604 is administered Though the beta-3-adrenergic receptor likely plays a role in fat loss secondary to AOD9604, at least one other mechanism must be in play as well
It was originally developed as a potential anti-obesity drug due to its ability to influence fat metabolism without causing the same growth-promoting effects associated with full HGH therapy (review)
Some Mc4 receptor agonists have been tested in preclinical and clinical studies
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