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Pernicious anemia Pernicious anemia has been estimated to affect approximately 2% to 3% of individuals over 65 years of age (5)
A further study performed in Canada estimated that switching patients established on IM B12 to the oral route could save the single province of Ontario between 1.4 and 9 million US Dollars over a 5-year period (Van Walraven et al., 2001)
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