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CBN is an agonist at TRPV1, TRPV2, TRPV3 and TRPV4 channels stimulating cell Ca 2+ influx with the activation of Ca 2+ -dependent pathways ( CBN has been identified as a potential analgesic and anti-inflammatory agent
10.1038/ng1362 304 ReddyP
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Examining the transition from adaptive to potentially harmful responses could offer further clarity in assessing carcinogenic risks
