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Most studies analyzed were single-arm, open-label investigations, underscoring the absence of RCTs necessary to establish definitive efficacy

The metabolites and lipids that were significantly different between ME/CFS and SC were tabulated (SOM Table S1), evaluated by KEGG pathways, and mapped to metabolic modules (Fig

The results of bacterial 16sRNA sequencing in mouse gastric tissues also confirmed the persistent colonization of H

This microbiota modulation is accompanied by significant amelioration of renal pathology, supporting the role of butyrate in regulating the gutimmunekidney axis to protect SLE target organs (154)