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Zhao M, Ralat MA, da Silva V, Garrett TJ, Melnyk S, James SJ, Gregory JF III (2013) Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells

Administration of these nanoparticles significantly decreased iron content and oxidative stress levels in the substantia nigra and striatum of PD mice and effectively reduced their dopaminergic neuron damage and as reversed their neurobehavioral deficits, without causing any overt adverse effects in the brain or other organs

PMID: 6576853

Routine bloodwork through a primary care provider can identify a deficiency early
