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Although the sample size was modest, it has allowed for observing several relevant associations, and it is in line with previous metabolomics research, because of the high cost of analyzing metabolomic profiles

Carnitine has been studied extensively because it is important to energy production and is a well-tolerated and generally safe therapeutic agent

nucleatum , which associates with impaired immunotherapy efficacy in both patients with CRC, as well as CRC-bearing mice, modulated immune cell recruitment and impaired anti-tumour immunity through the production of succinic acid in a mouse model of CRC 69

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