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10.1371/journal.pgen.1005241 51

Papaverine and Phentolamine may produce a painful, prolonged erection known as priapism
This leads to lactate accumulation and exacerbation of the Warburg effect, further aggravating hepatocyte injury, inflammation, and fibrosis, and driving the collapse of systemic lipid, glucose, and other metabolic processes (Cheng et al., 2025)

However, further research is required to decipher micronutrient deficiency-induced ROS generation, perception, and associated downstream signaling events, leading to the development of antioxidant responses in plants
