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The 10 ng/mL of IGF-1 remarkably increased collagen production, while the 10 and 20 ng/mL of IGF-1 treatment did not significantly increase collagen production compared to the untreated cells (Musson et al., 2017)

Natural or synthetic nootropics Nootropics can be of synthetic or natural origin

However, these symptoms usually take years to manifest, and fortunately, once diagnosed the deficiency is easily treated with vitamin B12 supplements

Slight reductions of glycolysis in ECs have also been shown to reduce its proliferation, migration and sprouting capacity (De Bock et al., 2013
