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Description
NNMT (Nicotinamide N-Methyltransferase) is a cytosolic enzyme that catalyses the transfer of a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide producing 1-methylnicotinamide (1-MNA) and S-adenosyl-homocysteine (SAH) as reaction products

Even some common medications, particularly those for managing acid reflux or diabetes, can interfere with this process over time

Role of the nitric oxide/cGMP pathway
In rare cases, some people may have an allergic reaction
