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MTHFR is vitamin B2 (riboflavin) dependent, and works to convert 5,10-methylenetetrahydrofolate (5,10-THF) to 5-Me-THF
The glycoprotein secreted Wnt ligand binds to Frizzled (Fz) and lipoprotein receptor-related protein (LRP) which act as co-receptors for Wnt protein
