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Various other modifications of the model could be designed to be consistent with experimental data, such as inhibition of glycolysis or mitochondrial respiration via specific inhibition of the ETC complex I
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doi: 10.1016/j.foodchem.2022.133461
Ferroptosis is defined by the preservation of functional cytoplasmic membranes, increased mitochondrial membrane density, decreased or absent cristae, increased release of oxidized PUFAs, elevated cytoplasmic levels of lipid ROS, and the process can be inhibited by iron chelators (Yang and Stockwell, 2008
