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Glutathione protects against oxidative stress caused by free radicals, is required for the immune system to operate properly, and is a powerful detoxifier.

ROS might act as a signaling molecule and activate the antioxidant proteins by interacting with signaling partners such as respiratory burst oxidase homolog (RBOH), G-proteins, Ca2+, mitogen activated protein kinases (MAPKs), and various transcription factors (TFs)

Biol Chem
