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Current guidelines recommend anti-CD38 antibody-based triplet combinations for relapsed/refractory disease after one to three prior lines of therapy, incorporating previously unused agents for lenalidomide- or bortezomib-refractory disease

Published mouse-to-human dose conversion factors typically apply factors of 12-15x reduction per kg

The injections are prescribed by a medical provider and given intramuscularly, or into the muscle

Vitamin B12 deficiency can also cause symptoms that affect the brain and nervous system (neurologic symptoms), including: Numbness Muscle weakness Mental health problems, ranging from mild depression or anxiety to confusion and dementia Balance and coordination issues Needles and pins Incontinence What is the best form of vitamin B12 to take