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Acknowledgements The authors thank Nick Rhodes from the Queensland Cyber Infrastructure Foundation (QCIF), Haojing Shao, and Enya Hermsen for their advice on bioinformatical analyses and computational assistance, Alastair McEwan and Mathias Jnsson for their editorial assistance on early drafts of the manuscript, and all members of the Degnan lab for their valuable discussions

Cyanide exists as the gas vapor of hydrogen cyanide (HCN) and cyanogen chloride (CNCl), which are liquid at room temperature

European Foundation for the Study of Chronic Liver Failure (EF Clif)

CTCF, CEBP, EGR, E-box, AP-1, MITF, and NRF motifs had enrichment in the ATAC-seq groups and the expression of genes encoding TF of these families were significantly upregulated (i.e