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Deregulated activation of c-Met contributes to a few aspects of tumor progression, such as inducing neoplastic cells to disaggregate from the tumor mass, eroding basement membranes, infiltrating stromal matrices, and finally colonizing new tissues to form metastases ( Onset Chronic liver diseases such as cirrhosis and hepatitis B or C are triggers of HCC (Janevska et al., 2015)

2nd, even though I can easily see the jumps in reasoning you come up with, I am not necessarily sure of how you appear to connect your ideas which inturn produce the actual final result

robust manufacturing includes inprocess controls, multistep purification (e.g., preparative HPLC), and final analytical release testing