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In addition, imaging modalities are expected to serve as an efficient and safe smart drug delivery system for the treatment of in situ metastases
Leugers CJ, Lee G (2010) Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding

These signals induce conformational alterations in nano-carriers, modulate the interactions between drugs and their carriers, and even disrupt the structural integrity of the carriers, thereby facilitating precise and controlled drug release [62, 63]
According to the FDA, compounding is generally a practice in which a pharmacist combines or alters ingredients in response to a prescription for an individual patient
