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Journal of Pharmaceutical Science 96 , 126, doi:10.1002/jps.20727 (2007)
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Autophagy is divided into three subtypes (macroautophagy (herein referred to as autophagy), chaperone-mediated autophagy (CMA), and microautophagy), which can be nonselective or selective [5] and include the selective removal of damaged mitochondria by mitophagy and the selective removal of endoplasmic reticulum components by phagocytosis [3, 5,6,7]

This suggests that the endocrine system may play a role