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By combining different immunogens on the same mosaic nanoparticle, we then tried to mitigate the anti-HVR1 response

PMID 2080048

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In a sepsis-induced AKI model, USP9x inhibits the ubiquitinated degradation of toll-like receptor 4 (TLR4), which is involved in inflammatory responses and apoptosis by activating the NF-B signaling pathway through interaction with lipopolysaccharide (LPS)