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The ability to stop myostatin from functioning could be useful in conditions like Duchenne muscle dystrophy (DMD) or in people who suffer muscle loss during prolonged immobility

Over-loss and muscle pooled SURMOUNT, BMI below 22 reached by about 7% (as early as week 12), toward about 15% by week 88 in the longest trial, clinical underweight under 0.4% (Almandoz 2026)

Another dosing recommendation begins with 1000 mcg daily for the first seven to 10 days, then 1000 mcg weekly for a month, followed by 1000 mcg monthly for life

This is a legitimate choice based on individual circumstances and risk-benefit analysis