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Research conducted only has animals as participants

Thus, prolonged methionine deprivation mitigates the cellular stress and oxidative damage that would otherwise lead to ferroptosis, providing a cellular protective mechanism against the induction of this form of cell death (Xue et al., 2023)

doi: 10.1038/s41418-018-0117-4

2 Oxidative stress and periodontitis 2.1 Basic concepts of oxidative stress Oxidative stress refers to an imbalance between the production of reactive oxygen types (involving superoxide anions, hydrogen peroxide, etc.) and other oxidants in the cellular and extracellular environment, capable of damaging cell structures and functions ( Under normal conditions, the body regulates and neutralizes these parlous oxidants by antioxidant systems (including superoxide dismutase, glutathione peroxidase, etc.), remaining redox balance within cells ( 2.2 Relationship between oxidative stress and gingival tissue inflammation Oxidative stress is very vital in the progress of periodontitis, tightly linked with inflammation of the gingival tissues