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Maybe re-look at the strengthening program and go from there
Aquaculture 438 , 7581 (2015)
By selectively disrupting key antioxidant systemssuch as inhibiting glutathione synthesis with buthionine sulfoximine (BSO), blocking thioredoxin reductase with auranofin, or directly targeting NRF2therapies can push cancer cells beyond their limited oxidative buffering capacity
This novel, nonenzymatic role for GSTs has direct relevance to the GST overexpressing phenotypes of many drug-resistant tumors
