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Annulus fissures are mechanically and chemically conducive to the ingrowth of nerves and blood vessels

Under hypoxia, accumulation of NADH is believed to provide more electrons for one-electron reduction of oxygen to O 2 (14)

Aneta Pilsova, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

According to NICE guidance and standard UK clinical practice, patients with confirmed B12 deficiency and neurological symptoms typically require initial treatment with hydroxocobalamin injections