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It is also known as lab-on-a-chip (LOC) technology which involves micro-devices that come with small chambers and channels [171]

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Contraindicated in patients with active malignancy, uncontrolled diabetes, or certain medical conditions

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In islet cells, the brain, and renal tubular cells, the reaction is directed primarily towards the oxidative deamination of glutamate because these cells and tissues contain high glutamate and low -KG/NH3 levels ( FIGURE 2 GDH aids in preserving the NH4 + concentration in the kidneys and several other organs (Treberg et al., 2010)

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