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259 In addition, the simultaneous knockout of HDAC3, HDAC5, and HDAC7 (class I and class II HDACs) resulted in the CDKN1A (p21) upregulation and inhibition of cell proliferation, 260 similar to p21 induction and cell cycle arrest in human mesenchymal stem cells after drug-induced inhibition of HDAC activity

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Lipotoxicity in Steatohepatitis Occurs Despite an Increase in Tricarboxylic Acid Cycle Activity
